Reference

The formulations named in the records

A formulation decides the shape of a bill before any program sets a price. A pellet is a visit. A patch is a 28-day supply. A gel can be dispensed for ninety days and billed by the month.

Checked Oct 23, 2026

Estradiol

7 formulations

Estradiol patch

Transdermal patch, changed twice weekly

A branded finished product applied to the skin. Four programs in the records price a patch, on cycles that run from a calendar month to a 12-week supply.

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Estradiol gel

Topical gel, measured by pump or sachet

A gel applied daily. No program in the current record set names a gel at the check date, so there is no priced record for it here.

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Estradiol spray

Transdermal spray

A spray applied to the forearm. It appears in program medication lists but has no priced record in this dataset yet.

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Estradiol tablet

Oral tablet

An oral tablet taken daily. Cheaper to dispense than a patch, and the record set is too thin to say how much that shows up in a program charge.

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Estradiol vaginal preparation

Vaginal tablet, cream or ring

A vaginal tablet, cream or ring. No program in the guide prices it separately at the check date, so it is bundled into a plan rather than shown as its own line. The record describes the route and the preparation and stops there: how a preparation is absorbed, and how it compares with an approved product, are clinical questions this guide does not answer.

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Estradiol pellet

Subcutaneous pellet, inserted in clinic

A pellet placed under the skin at a visit, releasing estradiol over roughly three months. It is the clearest case of a charge that is not monthly.

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Combined estradiol and progesterone plan

Two medicines, one plan

One membership billed for both medicines. The record carries estradiol as its medication class and lists progesterone as a product option.

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Not interchangeable

A compounded preparation is not an FDA-approved finished product and is not interchangeable with a branded one, even where the active ingredient is the same.

Last modified Oct 23, 2026